Neurobiological Factors
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There are a number of neurobiological factors that may contribute to Borderline Personality Disorder (BPD). Firstly, it has been found that levels of serotonin are typically much lower in clients with BPD than in others. Lowered serotonin levels has been linked to depression as well as to the control of impulses.
Amygdala
Studies that have analyzed the brain structure of those with BPD have found that the amygdala of these individuals generally show much higher rates of activation than in those individuals without BPD.
This difficulty with emotional regulation is also seen in other disorders showing the same characteristic over-activation of the amygdala, such as anxiety and mood disorders.
Amygdala
Studies that have analyzed the brain structure of those with BPD have found that the amygdala of these individuals generally show much higher rates of activation than in those individuals without BPD.
This difficulty with emotional regulation is also seen in other disorders showing the same characteristic over-activation of the amygdala, such as anxiety and mood disorders.
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Prefrontal Cortex
Some studies have also focused on the activity in the prefrontal cortex, understood to play a role in impulse control and reasoning. These studies show a lower level of functioning in these brain regions.
Normally, the amygdala and the prefrontal cortex are highly interconnected. However, in patients that have been diagnosed with BPD, we find that these connections are somewhat disrupted, which may also contribute to the notable issues with impulse control.
Some studies have also focused on the activity in the prefrontal cortex, understood to play a role in impulse control and reasoning. These studies show a lower level of functioning in these brain regions.
Normally, the amygdala and the prefrontal cortex are highly interconnected. However, in patients that have been diagnosed with BPD, we find that these connections are somewhat disrupted, which may also contribute to the notable issues with impulse control.